Elabscience

Caspase-3 Polyclonal Antibody

Product Code:
 
E-AB-66940
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using Caspase-3 Polyclonal Antibody at dilution of 1:1000.
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Immunohistochemistry of paraffin-embedded Human mammary cancer using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded Human colon carcinoma using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded Human gastric cancer using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded Mouse spleen using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
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Immunofluorescence analysis of NIH/3T3 cells using Caspase-3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of U-2OS cells using Caspase-3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines using Caspase-3 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human mammary cancer using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human gastric cancer using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse spleen using Caspase-3 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of NIH/3T3 cells using Caspase-3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2OS cells using Caspase-3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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E-AB-66940-60uL60uL£210.00
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E-AB-66940-120uL120uL£291.00
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E-AB-66940-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
Caspase-3
Background:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
31kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant protein of human Caspase-3.
ObservedMW:
31kDa
Purification method:
Affinity purification
Target Synonym:
CPP32;CPP32B;SCA-1;Active Caspase 3;CASP3;active Caspase-3;Caspase 3;Caspase-3 p12;caspase-3
UNIProt ID:
P42574

Documents