Elabscience

SLC25A27 Polyclonal Antibody

Product Code:
 
E-AB-66143
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using SLC25A27 Polyclonal Antibody at dilution of 1:1000.
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Immunofluorescence analysis of U-2 OS cells using SLC25A27 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines using SLC25A27 Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of U-2 OS cells using SLC25A27 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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E-AB-66143-60uL60uL£210.00
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E-AB-66143-120uL120uL£291.00
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E-AB-66143-200uL200uL£431.00
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Further Information

Abbreviation:
SLC25A27
Background:
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
27kDa/36kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human SLC25A27 (NP_001190981.1).
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
SLC25A27;UCP4
UNIProt ID:
O95847

Documents