Elabscience

BBC3 Polyclonal Antibody

Product Code:
 
E-AB-67059
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using BBC3 Polyclonal Antibody at dilution of 1:1000.
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Immunofluorescence analysis of NIH-3T3 cells using BBC3 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines using BBC3 Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of NIH-3T3 cells using BBC3 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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CodeSizePrice
E-AB-67059-60uL60uL£210.00
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E-AB-67059-120uL120uL£291.00
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E-AB-67059-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
BBC3
Background:
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
10kDa/14kDa/20kDa/26kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:100
Immunogen:
A synthetic peptide of human BBC3 (NP_001120713.1).
ObservedMW:
20kDa
Purification method:
Affinity purification
Target Synonym:
BBC3;JFY-1;JFY1;PUMA
UNIProt ID:
Q96PG8,Q9BXH1

Documents