Elabscience

KCNA1 Polyclonal Antibody

Product Code:
 
E-AB-67529
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of U-251MG cells using KCNA1 Polyclonal Antibody.
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Western blot analysis of extracts of U-251MG cells using KCNA1 Polyclonal Antibody.

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CodeSizePrice
E-AB-67529-60uL60uL£210.00
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E-AB-67529-120uL120uL£291.00
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E-AB-67529-200uL200uL£431.00
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Further Information

Abbreviation:
KCNA1
Background:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
56kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human KCNA1
ObservedMW:
56kDa
Purification method:
Affinity purification
Target Synonym:
KCNA1;AEMK;EA1;HBK1;HUK1;KV1.1;MBK1;MK1;RBK1
UNIProt ID:
Q09470

Documents