Elabscience

KCNN3 Polyclonal Antibody

Product Code:
 
E-AB-66196
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using KCNN3 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using KCNN3 Polyclonal Antibody at 1:1000 dilution.

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E-AB-66196-60uL60uL£210.00
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E-AB-66196-120uL120uL£291.00
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E-AB-66196-200uL200uL£431.00
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Further Information

Abbreviation:
KCNN3
Background:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
47kDa/48kDa/82kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant fusion protein of human KCNN3
ObservedMW:
50-85kDa
Purification method:
Affinity purification
Target Synonym:
KCNN3;KCa2.3;SK3;SKCA3;hSK3
UNIProt ID:
Q9UGI6

Documents