Elabscience

KLHL3 Polyclonal Antibody

Product Code:
 
E-AB-66137
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using KLHL3 Polyclonal Antibody at dilution of 1:3000.
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Western blot analysis of extracts of various cell lines using KLHL3 Polyclonal Antibody at dilution of 1:3000.

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CodeSizePrice
E-AB-66137-60uL60uL£210.00
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E-AB-66137-120uL120uL£291.00
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E-AB-66137-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
KLHL3
Background:
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
55kDa/61kDa/64kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human KLHL3 (NP_059111.2).
ObservedMW:
75kDa
Purification method:
Affinity purification
Target Synonym:
KLHL3;PHA2D
UNIProt ID:
Q9UH77

Documents