Elabscience

NF1 Polyclonal Antibody

Product Code:
 
E-AB-53528
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NF1 Polyclonal Antibody at dilution of 1:65(?200)
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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NF1 Polyclonal Antibody at dilution of 1:65(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NF1 Polyclonal Antibody at dilution of 1:65(?200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NF1 Polyclonal Antibody at dilution of 1:65(?200)

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E-AB-53528-20uL20uL£125.00
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E-AB-53528-60uL60uL£172.00
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E-AB-53528-120uL120uL£237.00
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E-AB-53528-200uL200uL£344.00
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Further Information

Abbreviation:
NF1
Background:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:250, ELISA 1:500-1000
Immunogen:
Synthetic peptide of human NF1
Purification method:
Antigen affinity purification
Target Synonym:
DKFZp686J1293;FLJ21220;Neurofibromatosis Noonan syndrome;Neurofibromatosis related protein NF 1;Neurofibromatosis related protein NF1;neurofibromatosis type I;Neurofibromatosis-related protein NF-1;Neurofibromin 1;Neurofibromin truncated;Neurofibromin1;NF 1;NF;NF1;NF1;NFNS;Type 1 Neurofibromatosis;von Recklinghausen disease neurofibromin;von Recklinghausen disease related protein VRNF;VRNF;WATS;Watson disease related protein WSS;Watson syndrome;WSS
UNIProt ID:
P21359

Documents