Elabscience

PDHA1 Polyclonal Antibody

Product Code:
 
E-AB-52930
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of A549 Hela and HepG2 cell lysates using PDHA1 Polyclonal Antibody at dilution of 1:750
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PDHA1 Polyclonal Antibody at dilution of 1:50(?200)
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Western blot analysis of A549 Hela and HepG2 cell lysates using PDHA1 Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PDHA1 Polyclonal Antibody at dilution of 1:50(?200)

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E-AB-52930-20uL20uL£125.00
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E-AB-52930-120uL120uL£237.00
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E-AB-52930-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
PDHA1
Background:
PDHA1(Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial) is also named as PHE1A.It is one of the 3 enzymes of the pyruvate dehydrogenase complex which is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA.It has 4 isoforms produced by alternative splicing.Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
43 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PDHA1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ODPA;PDH;PDHA;PDHA1;PDHCE1A;PDHE1 A type I;PDHE1-A type I;PHE1A;Pyruvate Dehydrogenase (lipoamide) alpha 1;Pyruvate dehydrogenase complex;E1 alpha polypeptide 1;Pyruvate Dehydrogenase E1 alpha;Pyruvate dehydrogenase E1 component subunit alpha;somatic form;mitochondrial
UNIProt ID:
P08559

Documents

References

  • https://www.sciencedirect.com/science/article/pii/S0044848621015210