Elabscience

IGHA1 Polyclonal Antibody

Product Code:
 
E-AB-52649
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using IGHA1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using IGHA1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using IGHA1 Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using IGHA1 Polyclonal Antibody at dilution of 1:50(?200)

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E-AB-52649-20uL20uL£125.00
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E-AB-52649-60uL60uL£172.00
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E-AB-52649-120uL120uL£237.00
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E-AB-52649-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
IGHA1
Background:
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human IGHA1
Purification method:
Antigen affinity purification
Target Synonym:
FLJ14473;FLJ35065;FLJ35500;FLJ36402;FLJ39698;FLJ40001;FLJ41548;FLJ41552;FLJ41789;FLJ43248;FLJ43594;FLJ44293;FLJ46028;FLJ46621;FLJ46724;FLJ46811;FLJ46824;FLJ90170;Ig alpha 1 chain C region;IgA1;IGHA1;immunoglobulin heavy constant alpha 1;MGC102857
UNIProt ID:
P01876

Documents