Elabscience

IL17A Polyclonal Antibody

Product Code:
 
E-AB-17917
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using IL17A Polyclonal Antibody at dilution of 1:40(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using IL17A Polyclonal Antibody at dilution of 1:40(?200)

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E-AB-17917-20uL20uL£125.00
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E-AB-17917-60uL60uL£172.00
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E-AB-17917-120uL120uL£237.00
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E-AB-17917-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
IL17A
Background:
IL17A,also named as IL-17,is a proinflammatory cytokine. IL-17,synthesized only by memory T cells and natural killer cells,has pleiotropic effects,mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2),as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis,psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein,that is widely expressed on epithelial cells,fibroblasts,B and T cells,and monocytic cells. In psoriatic skin lesions,both Th17 cells and their downstream effector molecules,e.g. IL-17 and IL-22,are highly increased.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human IL17A
Purification method:
Antigen affinity purification
Target Synonym:
CTLA 8;CTLA-8;CTLA8;Cytotoxic T lymphocyte associated antigen 8;Cytotoxic T lymphocyte associated protein 8;Cytotoxic T lymphocyte associated serine esterase 8;Cytotoxic T-lymphocyte-associated antigen 8;IL 17A;IL-17;IL-17A;IL17;IL17;Il17a;Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8);Interleukin 17A;Interleukin-17A;Interleukin17;Interleukin17A;OTTHUMP00000016597;OTTMUSP00000046003
UNIProt ID:
Q16552

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