Elabscience

Recombinant Klebsiella pneumoniae NEO Protein

Product Code:
 
PKSQ050062
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Bacteria
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSQ050062-10ug10ug£297.00
Quantity:
PKSQ050062-50ug50ug£498.00
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This product comes from: China.
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Further Information

Abbreviation:
NEO
Accession:
P00552
Background:
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
Calculated MW:
29 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 6%Trehalose, 4%Mannitol, 0.05%Tween80, PH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
28-30 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Phe264
Target Synonym:
Aminoglycoside 3'-phosphotransferase;APH(3')-II;APH(3')II;Kanamycin kinase type II;Neomycin-kanamycin phosphotransferase type II;neo
UNIProt ID:
P00552

Documents