Elabscience

TLR2 Polyclonal Antibody

Product Code:
 
E-AB-63499
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Mouse islets of langerhans using TLR2 Polyclonal Antibody at dilution of 1:150 (40x lens).
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Immunofluorescence analysis of Rat lung using TLR2 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded Mouse islets of langerhans using TLR2 Polyclonal Antibody at dilution of 1:150 (40x lens).
Immunofluorescence analysis of Rat lung using TLR2 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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E-AB-63499-60uL60uL£210.00
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E-AB-63499-120uL120uL£291.00
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E-AB-63499-200uL200uL£431.00
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Further Information

Abbreviation:
TLR2
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:50-1:100
Immunogen:
A synthetic peptide of human TLR2
Purification method:
Affinity purification
Target Synonym:
CD282;TIL4;TLR2
UNIProt ID:
O60603

Documents