Elabscience

TFPI Polyclonal Antibody

Product Code:
 
E-AB-64303
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using TFPI Polyclonal Antibody at dilution of 1:3000.
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Western blot analysis of extracts of various cell lines using TFPI Polyclonal Antibody at dilution of 1:3000.

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E-AB-64303-60uL60uL£210.00
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E-AB-64303-120uL120uL£291.00
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E-AB-64303-200uL200uL£431.00
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  • Further Information
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Further Information

Abbreviation:
TFPI
Background:
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
28kDa/35kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant fusion protein of human TFPI (NP_001027452.1).
ObservedMW:
32kDa
Purification method:
Affinity purification
Target Synonym:
TFPI;EPI;LACI;TFI;TFPI1
UNIProt ID:
P10646

Documents

References

  • https://www.hindawi.com/journals/omcl/2020/7691352/