Elabscience

PTPN11 Polyclonal Antibody

Product Code:
 
E-AB-60785
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human gastric cancer using PTPN11 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Human gastric cancer using PTPN11 Polyclonal Antibody at dilution of 1:100 (40x lens).

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E-AB-60785-60uL60uL£210.00
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E-AB-60785-120uL120uL£291.00
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E-AB-60785-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PTPN11
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human PTPN11 (NP_002825.3).
Purification method:
Affinity purification
Target Synonym:
BPTP3;CFC;JMML;METCDS;NS1;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SHP2;PTPN11
UNIProt ID:
Q06124

Documents