Elabscience

Purified Anti-Mouse/Human CD11b Antibody[M1/70]

Product Code:
 
E-AB-F1081A
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clone:
 
M1/70
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C. Do not freeze.
 

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CodeSizePrice
E-AB-F1081A-25ug25ug£87.00
Special offer! Buy 2 Get 1 Free on selected Elabscience Flow Cytometry Antibodies. Read more here.
Quantity:
E-AB-F1081A-100ug100ug£111.00
Special offer! Buy 2 Get 1 Free on selected Elabscience Flow Cytometry Antibodies. Read more here.
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Further Information

Abbreviation:
CD11b
Background:
CD11b is < 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
GeneID:
164,093,684
Target Synonym:
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
UNIProt ID:
P05555;P11215;
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 0.125 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Documents

References

  • https://www.sciencedirect.com/science/article/pii/S1567576920338145