Elabscience

MMP13 Polyclonal Antibody

Product Code:
 
E-AB-60365
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using MMP13 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using MMP13 Polyclonal Antibody at dilution of 1:1000.

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E-AB-60365-120uL120uL£291.00
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E-AB-60365-200uL200uL£431.00
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  • Further Information
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Further Information

Abbreviation:
MMP13
Background:
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
53kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MMP13 (NP_002418.1).
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
MMP13;CLG3;MANDP1;MDST;MMP-13
UNIProt ID:
P45452

Documents

References

  • https://www.frontiersin.org/articles/10.3389/fcell.2021.641529/full
  • https://www.sciencedirect.com/science/article/pii/S0753332218350662