Elabscience

BEST1 Polyclonal Antibody

Product Code:
 
E-AB-64917
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using BEST1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using BEST1 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-64917-60uL60uL£210.00
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E-AB-64917-120uL120uL£291.00
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E-AB-64917-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
BEST1
Background:
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
57kDa/67kDa/69kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human BEST1
ObservedMW:
68kDa
Purification method:
Affinity purification
Target Synonym:
BEST1;ARB;BEST;BMD;RP50;TU15B;VMD2
UNIProt ID:
O76090

Documents