Elabscience

CASP3 Monoclonal Antibody

Product Code:
 
E-AB-22213
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
Clone:5H10
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human skin tissue using CASP3 Monoclonal Antibody at dilution of 1:200.
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Immunohistochemistry of paraffin-embedded Human prostate tissue using CASP3 Monoclonal Antibody at dilution of 1:200.
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Immunohistochemistry of paraffin-embedded Human skin tissue using CASP3 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human prostate tissue using CASP3 Monoclonal Antibody at dilution of 1:200.

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E-AB-22213-20uL20uL£125.00
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E-AB-22213-60uL60uL£172.00
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E-AB-22213-120uL120uL£237.00
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E-AB-22213-200uL200uL£344.00
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Further Information

Abbreviation:
CASP3
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-200
Immunogen:
Synthetic Peptide of Caspase-3
Purification method:
Protein A purification
Target Synonym:
A830040C14Rik;Apopain;CASP-3;CASP3;CASP3;Casp3a;Caspase 3;Caspase 3;apoptosis-related cysteine peptidase;Caspase 3;apoptosis-related cysteine protease;Caspase 3;apoptosis-related cysteine protease a;Caspase-3 subunit p12;CC3;CPP-32;CPP32;CPP32B;Cysteine protease CPP32;EC 3.4.22.56;LICE;mldy;OTTHUMP00000165052;OTTHUMP00000165053;OTTHUMP00000165054;PARP cleavage protease;Procaspase3;Protein Yama;SCA 1;SCA-1;SREBP cleavage activity 1;Yama
UNIProt ID:
P42574

Documents