Elabscience

VWA5A Polyclonal Antibody

Product Code:
 
E-AB-10998
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using VWA5A Polyclonal Antibody at dilution 1:80
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using VWA5A Polyclonal Antibody at dilution 1:80
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Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using VWA5A Polyclonal Antibody at dilution 1:80
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using VWA5A Polyclonal Antibody at dilution 1:80

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E-AB-10998-20uL20uL£125.00
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E-AB-10998-60uL60uL£172.00
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E-AB-10998-120uL120uL£237.00
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E-AB-10998-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
VWA5A
Background:
VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant protein of human VWA5A
Purification method:
Affinity purification
Target Synonym:
BCSC1;BCSC-1;LOH11CR2A
UNIProt ID:
O00534

Documents