Elabscience

SLC22A17 Polyclonal Antibody

Product Code:
 
E-AB-12870
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human brain tissue using SLC22A17 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human brain tissue using SLC22A17 Polyclonal Antibody at dilution 1:40

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E-AB-12870-20uL20uL£125.00
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E-AB-12870-120uL120uL£237.00
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E-AB-12870-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
SLC22A17
Background:
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Synthetic peptide of human SLC22A17
Purification method:
Affinity purification
Target Synonym:
24p3 receptor;24p3R;BOCT;BOIT;Brain type organic cation transporter;Brain-type organic cation transporter;hBOIT;Lipocalin-2 receptor;Neutrophil gelatinase associated lipocalin receptor;Neutrophil gelatinase-associated lipocalin receptor;NGAL receptor;NgalR;NGALR2;NGALR3;OTTHUMP00000082690;OTTHUMP00000082691;Potent brain type organic ion transporter;S22AH;Slc22a17;Solute carrier family 22 member 17;Solute carrier family 22 organic cation transporter member 17
UNIProt ID:
Q8WUG5

Documents