Elabscience

RNF185 Polyclonal Antibody

Product Code:
 
E-AB-91452
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of Mouse testis using RNF185 Polyclonal Antibody at1:1000 dilution.
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Western blot analysis of extracts of Mouse testis using RNF185 Polyclonal Antibody at1:1000 dilution.

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CodeSizePrice
E-AB-91452-60uL60uL£210.00
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E-AB-91452-120uL120uL£291.00
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E-AB-91452-200uL200uL£431.00
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Further Information

Abbreviation:
RNF185
Background:
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER-associated degradation (ERAD pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
14kDa/20kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human RNF185
ObservedMW:
20kDa
Purification method:
Affinity purification
Target Synonym:
RNF185
UNIProt ID:
Q96GF1

Documents