CDK5 Polyclonal Antibody

CDK5

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

29kDa/33kDa

1mg/mL

Unconjugated

WB 1:500-1:2000

Recombinant fusion protein of human CDK5

33kDa

Affinity purification

CDK5;LIS7;PSSALRE

Q00535