Elabscience

SLC8A1 Polyclonal Antibody

Product Code:
 
E-AB-92655
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of Mouse brain using SLC8A1 Polyclonal Antibody at 1:5000 dilution.
2 / 3
Immunohistochemistry of paraffin-embedded mouse spleen using SLC8A1 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
3 / 3
Immunohistochemistry of paraffin-embedded rat stomach using SLC8A1 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
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Western blot analysis of extracts of Mouse brain using SLC8A1 Polyclonal Antibody at 1:5000 dilution.
Immunohistochemistry of paraffin-embedded mouse spleen using SLC8A1 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded rat stomach using SLC8A1 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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E-AB-92655-60uL60uL£210.00
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E-AB-92655-120uL120uL£291.00
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E-AB-92655-200uL200uL£431.00
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Further Information

Abbreviation:
SLC8A1
Background:
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
104kDa/107kDa/108kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human SLC8A1
ObservedMW:
100KDa
Purification method:
Affinity purification
Target Synonym:
SLC8A1;NCX1
UNIProt ID:
P32418

Documents