Elabscience

Recombinant Human APE1/APE Protein (His Tag)

Product Code:
 
PKSH030851
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
PKSH030851-100ug100ug£763.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
APE1;APE
Accession:
P27695
Background:
The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease; DNA 3' repair diesterase; 3'-5' exonuclease and DNA 3'-phosphatase activities.Although Apex mRNA was expressed ubiquitously; the levels varied significantly; suggesting organ- or tissue-specific expression of the Apex gene. The highest level was observed in the testis; relatively high levels in the thymus; spleen; kidney and brain; and the lowest level in the liver in rats. However; the present results suggested that APEX/Ref-1 gene product can interact with AP-1 binding proteins in brain; especially in the hippocampal formation; to regulate some brain functions by redox-activation.
Calculated MW:
37 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
37 kDa
Purity:
> 92 % as determined by reducing SDS-PAGE.
Sequence:
Pro2-Leu 318
Target Synonym:
DNA-(Apurinic or Apyrimidinic Site) Lyase;APEX Nuclease;APEN;Apurinic-Apyrimidinic Endonuclease 1;AP Endonuclease 1;APE-1REF-1;Redox Factor-1;APEX1;APE;APE1;APEX;APX;HAP1;REF1
UNIProt ID:
P27695

Documents