NSJ Bioreagents

NKX2.2 Antibody

Product Code:
 
NSJ-V3314SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC testing of FFPE Ewings sarcoma with NKX2.2 antibody. HIER: steam sections in 10mM citrate buffer, pH 6.0, for 10-20 min.
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IHC testing of FFPE Ewings sarcoma with NKX2.2 antibody. HIER: steam sections in 10mM citrate buffer, pH 6.0, for 10-20 min.

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NSJ-V3314SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Titering of the NKX2.2 antibody may be required for optimal performance.
Description:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Gene ID #:
4821
Immunogen:
A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
Limitation:
This NKX2.2 antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein A affinity chromatography
Uniprot #:
O95096

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