NSJ Bioreagents

CYP2D6 Antibody

Product Code:
 
NSJ-R36473
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Caprine (Goat)
Antibody Isotype:
 
Goat Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store the CYP2D6 antibody at -20oC.
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Western blot testing of human liver lysate with CYP2D6 antibody at 2ug/ml. Predicted molecular weight ~56 kDa.
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Western blot testing of human liver lysate with CYP2D6 antibody at 2ug/ml. Predicted molecular weight ~56 kDa.

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CodeSizePrice
NSJ-R36473-100UG100 ug£535.00
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Further Information

Application Details:
Western blot: 1-3ug/ml,ELISA (peptide) LOD: 1:1000
Application Note:
Optimal dilution of the CYP2D6 antibody should be determined by the researcher.
Description:
CYP2D6, a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. In particular, CYP2D6 is responsible for the metabolism and elimination of approximately 25% of clinically used drugs, via the addition or removal of certain functional groups ? specifically, hydroxylation, demethylation, and dealkylation ? at various points along a substrate's core structure. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. [Wiki]
Format:
Antigen affinity purified
Formulation:
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Immunogen:
Amino acids PTGQPRPSHH were used as the immunogen for this CYP2D6 antibody.
Limitation:
This CYP2D6 antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
P10635

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