Diaclone

Mouse Anti-Human CD10 BioActive Antibody, Clone B-E3, Azide free

Product Code:
 
854.090.000
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B-E3
Regulatory Status:
 
RUO
Target Species:
 
Human
 

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854.090.000200ug/200ul£232.00
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  • Further Information
  • References
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Further Information

Activity:
Cytotoxic In association with rabbit complement on CD10+ cells
Antigen:
CD10
Antigen Synonyms:
CALLA
Biological Acivity:
Cytotoxic In association with rabbit complement on CD10+ cells
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Daudi and Raji cell lines
Reactivity:
Human
Research Area:
B Cell AntigensCD Markers
Specificity:
Recognises the Common Acute Lymphoblastic Leukemia Antigen (CALLA) a 100 kDa protein

References

  1. Geijtenbeek T. B. et al. Blood1999; 94(2): 754-64.. High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia. https://www.ncbi.nlm.nih.gov/pubmed/10397743
  2. van den Berg T. K. et al. J Immunol;1996; 157(7): 3130-8.. Regulation of sialoadhesin expression on rat macrophages. Induction by glucocorticoids and enhancement by IFN-beta IFN-gamma IL-4 and lipopolysaccharide. https://www.ncbi.nlm.nih.gov/pubmed/8816424
  3. Pan C. et al. Cancer Res.2003; 63(17): 5526-31.. CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors. https://www.ncbi.nlm.nih.gov/pubmed/14500390