ELK Biotechnology

Recombinant Mouse IL-2

Product Code:
 
ELK-EPT026
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature.
Storage:
 
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
ELK-EPT026-10ug10ug£195.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
P04351
Alternative Names:
aldesleukin; interleukin 2; interleukin-2; IL-2; IL2; T-cell growth facter; T cell growth factor; TCGF
Apparent Molecular Weight:
17 KDa, reducing conditions
Background:
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL?2 shares 56% and 73% aa sequence identity with human and rat IL?2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL?2 may be a key cytokine in the natural suppression of autoimmunity.
Biological Activity:
Loaded Human IL-2RA-Fc(Cat#CJ78) on Protein A Biosensor, can bind Mouse IL-2(Cat#CK24) with an affinity constant of 0.17 uM as determined in BLI assay.?
Endotoxin:
Less than 0.001 ng/ug (0.01 EU/ug) as determined by LAL test.
Molecular Weight:
17.4 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Redissolve:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.?