ELK Biotechnology

Recombinant Mouse Thrombomodulin (C-6His)

Product Code:
 
ELK-EPT230
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped on dry ice/polar packs.
Storage:
 
Store at -70°C, stable for 6 months after receipt. Store at -70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
ELK-EPT230-10ug10ug£324.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
P15306
Alternative Names:
Thrombomodulin; TM; Fetomodulin; CD141; BDCA-3; Thbd
Apparent Molecular Weight:
85-90 KDa, reducing conditions
Background:
Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). In addition, THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Molecular Weight:
54.6 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.