NSJ Bioreagents

MCC Antibody / Mutated in Colorectal Cancers (Antigen affinity purified)

Product Code:
 
NSJ-RQ6655
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Mutated in Colorectal Cancers antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of human HeLa cells with Mutated in Colorectal Cancers antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mutated in Colorectal Cancers antibody.~
2 / 2
Western blot testing of 1)

Flow cytometry testing of human HeLa cells with Mutated in Colorectal Cancers antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mutated in Colorectal Cancers antibody.~
Western blot testing of 1)

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NSJ-RQ6655-100ug100ug£535.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the Mutated in Colorectal Cancers antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
MUTATED IN COLORECTAL CANCERS (MCC) is a tumor suppressor gene. It is mapped to 5q22.2. This gene suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. MCC also Inhibits DNA binding of b-catenin/TCF/LEF transcription factors, and it is Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation. What's more, MCC can interact with SCRIB (via phosphorylated PDZ-binding motif), EZR, SNX27, SLC9A3R1 and SLC9A3R2.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Recombinant human protein (amino acids M1-E234) was used as the immunogen for the Mutated in Colorectal Cancers antibody.
Limitation:
This Mutated in Colorectal Cancers antibody is available for research use only.
Purity:
Antigen affinity purified
Uniprot #:
P23508

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