NSJ Bioreagents

TIMP2 Antibody

Product Code:
 
NSJ-V4548
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
TIMP2/8193R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the TIMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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IHC staining of FFPE human bladder carcinoma tissue with TIMP2 antibody (clone TIMP2/8193R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
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Negative control: IHC testing of FFPE hum
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IHC staining of FFPE human bladder carcinoma tissue with TIMP2 antibody (clone TIMP2/8193R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
Negative control: IHC testing of FFPE hum

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CodeSizePrice
NSJ-V4548-20UG20 ug£264.00
Quantity:
NSJ-V4548-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant fragment of human TIMP2 protein was used as the immunogen for the TIMP2 antibody.
Limitation:
This TIMP2 antibody is available for research use only.
Localization:
Cytoplasm, Cell surface, Secreted
Purity:
Protein A/G affinity
Uniprot #:
P16035

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