NSJ Bioreagents

PAX4 Antibody

Product Code:
 
NSJ-V5215SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PAX4/3011
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot the PAX4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 1
SDS-PAGE analysis of purified, BSA-free PAX4 antibody (clone PAX4/3011) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free PAX4 antibody (clone PAX4/3011) as confirmation of integrity and purity.

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NSJ-V5215SAF-100UG100 ug£534.00
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Further Information

Application Details:
ELISA (Order BSA-free format for coating)
Description:
Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet beta cell lines MIN6, beta TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the PAX4 antibody.
Limitation:
This PAX4 antibody is available for research use only.
Localization:
Nucleus
Purity:
Protein A/G affinity
Uniprot #:
O43316

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