TargetMol

BRD 4354 ditrifluoroacetate

Product Code:
 
TAR-T10602
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T10602-1mL1 mL * 10 mM (in DMSO)Enquire
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Further Information

Bioactivity:
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 uM).
CAS:
T10602
Formula:
C25H25ClF6N4O5
Molecular Weight:
610.93
Pathway:
DNA Damage/DNA Repair|Chromatin/Epigenetic
Purity:
0.98
SMILES:
OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Target:
HDAC

Documents

References

Boskovic ZV, ET AL. Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.