AdipoGen Life Sciences

IL-7 (mouse) (monomeric):Fc (LALA-PG)-KIH (human) (rec.)

Product Code:
 
AG-40B-0256
Product Group:
 
Recombinant Proteins
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Shipping:
 
BI
Storage:
 
Short term: +4°C. Long term: -20°C.
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AG-40B-0256-C05050 ug£380.00
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Further Information

Accession Number:
P10168
Biological Activity:
Activates CD4+?T Cells proliferation.?The Fc contains the mutations LALA-PG that abolish the interaction between the Fc and Fc?Rs and therefore Fc undesirable effects.
Concentration:
After reconstitution: 1mg/ml
Crossreactivity:
Mouse
Endotoxin Content:
<0.01EU/ug protein (LAL test).
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions.
Molecular Weight:
~55kDa and 28kDa (SDS-PAGE)
Purity:
>95% (SDS-PAGE)
Reconstitution:
Reconstitute with 50ul endotoxin-free water.
Sequence:
Mouse IL-7 (aa 26-154) is fused at the C-terminus to the Fc portion of human IgG1 (LALA-PG) (Knobs-into-Holes technology) (see reference: J.B. Ridgway, et al.; Protein Eng.?9,?617 (1996)).
Source/Host:
HEK 293 cells. Produced using animal component-free medium.
Specificity:
Binds to mouse IL-7R.?Fc (LALA-PG)-KIH (human) does not bind to FcRs.
Synonyms:
IL-7 (mouse) (monomeric):Fc (LALA-PG) Knobs-into-Holes (human) (rec.); Interleukin-7
Use/Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

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