NSJ Bioreagents

Wee1 Antibody

Product Code:
 
NSJ-F54097
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the Wee1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of Wee1 antibody at 1:2000: Lane 1) human HeLa, 2) Jurkat and 3) K562 cell lysate. Predicted molecular weight ~72 kDa.
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Western blot testing of Wee1 antibody at 1:2000: Lane 1) human HeLa, 2) Jurkat and 3) K562 cell lysate. Predicted molecular weight ~72 kDa.

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CodeSizePrice
NSJ-F54097-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54097-0.2ML0.2 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details:
WB: 1:2000
Description:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. [UniProt]
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 96-130 from human Wee1 was used as the immunogen for the Wee1 antibody.
Purity:
Antigen affinity
Uniprot #:
P30291