NSJ Bioreagents

HACE1 Antibody

Product Code:
 
NSJ-F54120
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
1854CT757.66.47
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the HACE1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of HACE1 antibody at 1:2000: Lane 1) human HEK293 and 2) 293T/17 cell lysate. Predicted molecular weight ~102 kDa.
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Western blot testing of HACE1 antibody at 1:2000: Lane 1) human HEK293 and 2) 293T/17 cell lysate. Predicted molecular weight ~102 kDa.

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CodeSizePrice
NSJ-F54120-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54120-0.2ML0.2 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
WB: 1:2000
Description:
HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 is an E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB. [UniProt]
Format:
Purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
Recombinant human HACE1 was used as the immunogen for the HACE1 antibody.
Purity:
Protein G purified
Uniprot #:
Q8IYU2