NSJ Bioreagents

ERAB Antibody / HSD17B10 (N-Terminal Region)

Product Code:
 
NSJ-F54127
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the ERAB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of ERAB antibody at 1:8000: Lane 1) human HeLa, 2) HepG2, 3) Jurkat, 4) K562 and 5) SH-SY5Y cell lysate. Predicted molecular weight ~27 kDa.
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Western blot testing of ERAB antibody at 1:8000: Lane 1) human HeLa, 2) HepG2, 3) Jurkat, 4) K562 and 5) SH-SY5Y cell lysate. Predicted molecular weight ~27 kDa.

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CodeSizePrice
NSJ-F54127-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54127-0.2ML0.2 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details:
WB: 1:8000
Description:
ERAB / HSD17B10 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). [UniProt]
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 14-48 from human ERAB was used as the immunogen for the ERAB antibody.
Purity:
Antigen affinity
Uniprot #:
Q99714