NSJ Bioreagents

BIRC6 Antibody (C-Terminal Region)

Product Code:
 
NSJ-F54131
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the BIRC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of BIRC6 antibody at 1:1000: Lane 1) huamn SH-SY5Y and 2) HeLa cell lysate. Predicted molecular weight ~530 kDa.
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Western blot testing of BIRC6 antibody at 1:1000: Lane 1) huamn SH-SY5Y and 2) HeLa cell lysate. Predicted molecular weight ~530 kDa.

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CodeSizePrice
NSJ-F54131-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54131-0.2ML0.2 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details:
WB: 1:1000
Description:
Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.
Purity:
Antigen affinity
Uniprot #:
Q9NR09