NSJ Bioreagents

RNF20 Antibody / BRE1A

Product Code:
 
NSJ-RQ7632
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
3C6E2
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the RNF20 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of 1) human HeLa, 2) human MOLT4, 3) human 293T, 4) human A431, 5) rat brain and 6) mouse brain tissue lysate with RNF20 antibody. Predicted molecular weight ~114 kDa.
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Western blot testing of 1) human HeLa, 2) human MOLT4, 3) human 293T, 4) human A431, 5) rat brain and 6) mouse brain tissue lysate with RNF20 antibody. Predicted molecular weight ~114 kDa.

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NSJ-RQ7632-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids E123-S389) was used as the immunogen for the RNF20 antibody.
Purity:
Antigen affinity purified
Uniprot #:
Q5VTR2