WFS1 Antibody / Wolframin

Product Code:

NSJ-RQ7878

Product Group:

Primary Antibodies

Supplier:

NSJ Bioreagents

Host Type:

Rabbit

Antibody Isotype:

Rabbit IgG

Antibody Clonality:

Polyclonal

Regulatory Status:

RUO

Target Species:

Human

Applications:

Enzyme-Linked Immunosorbent Assay (ELISA)
Western Blot (WB)

Storage:

After reconstitution, the WFS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

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Code	Size	Price

NSJ-RQ7878-100ug

100 ug

£535.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Application Details:

Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml

Buffer:

Lyophilized from 1X PBS with 2% Trehalose

Description:

Wolframin is a protein that in humans is encoded by the WFS1 gene. This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

Format:

Antigen affinity purified

Formulation:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Immunogen:

E. coli-derived recombinant human protein (amino acids D272-K876) was used as the immunogen for the WFS1 antibody.

Purity:

Antigen affinity purified

Uniprot #:

O76024