NSJ Bioreagents

PAN2 Antibody / PAN deadenylation complex subunit 2 / USP52

Product Code:
 
NSJ-RQ8005
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the PAN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of fixed and permeabilized human PC-3 cells with PAN2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= PAN2 antibody.
2 / 2
Western blot testing of 1) human HepG2, 2) human HEL, 3) human Daudi, 4) rat PC-12, 5) mouse thymus and 6) mouse NIH 3T3 cell lysate with PAN2 antibody. Predicted molecular weight ~135 kDa.
❮❯

Flow cytometry testing of fixed and permeabilized human PC-3 cells with PAN2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= PAN2 antibody.
Western blot testing of 1) human HepG2, 2) human HEL, 3) human Daudi, 4) rat PC-12, 5) mouse thymus and 6) mouse NIH 3T3 cell lysate with PAN2 antibody. Predicted molecular weight ~135 kDa.

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CodeSizePrice
NSJ-RQ8005-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Description:
PAB-dependent poly(A)-specific ribonuclease subunit 2, also called Inactive ubiquitin carboxyl-terminal hydrolase 52 (USP52), is an enzyme that in humans is encoded by the PAN2 gene. This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids M1-L356) was used as the immunogen for the PAN2 antibody.
Purity:
Antigen affinity purified
Uniprot #:
Q504Q3