NSJ Bioreagents

FOXO3A Antibody

Product Code:
 
NSJ-RQ8018
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the FKHRL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of human 1) HeLa, 2) Jurkat, 3) PC-3 and 4) 293T cell lysate with FKHRL1 antibody. Expected molecular weight: 71-90 kDa depending on glycosylation level.
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Western blot testing of human 1) HeLa, 2) Jurkat, 3) PC-3 and 4) 293T cell lysate with FKHRL1 antibody. Expected molecular weight: 71-90 kDa depending on glycosylation level.

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CodeSizePrice
NSJ-RQ8018-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Description:
Forkhead box O3, also known as FKHRL1 (Forkhead in rhabdomyosarcoma-like 1) or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids R312-Q537) was used as the immunogen for the FKHRL1 antibody.
Purity:
Antigen affinity purified
Uniprot #:
O43524