NSJ Bioreagents

SERPIND1 Antibody / Heparin cofactor 2 / HC-II

Product Code:
 
NSJ-RQ8122
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Heparin cofactor 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of fixed and permeabilized human 293T cells with Heparin cofactor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Heparin cofactor 2 antibody.
2 / 2
Western blot testing of human 1) 293T and 2) HepG2 cell lysate with Heparin cofactor 2 antibody. Predicted molecular weight ~57 kDa but may be observed at higher molecular weights due to glycosylation.
❮❯

Flow cytometry testing of fixed and permeabilized human 293T cells with Heparin cofactor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Heparin cofactor 2 antibody.
Western blot testing of human 1) 293T and 2) HepG2 cell lysate with Heparin cofactor 2 antibody. Predicted molecular weight ~57 kDa but may be observed at higher molecular weights due to glycosylation.

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-RQ8122-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Show All

Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Description:
Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate (minor antithrombin). This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids D90-S499) was used as the immunogen for the Heparin cofactor 2 antibody.
Purity:
Antigen affinity purified
Uniprot #:
P05546