NSJ Bioreagents

ABCC3 Antibody / MRP3

Product Code:
 
NSJ-RQ8175
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the MRP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of fixed and permeabilized human HepG2 cells with MRP3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MRP3 antibody.
2 / 2
Western blot testing of human HepG2 cell lysate with MRP3 antibody. Predicted molecular weight ~169 kDa but may be observed at higher molecular weights due to glycosylation.
❮❯

Flow cytometry testing of fixed and permeabilized human HepG2 cells with MRP3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= MRP3 antibody.
Western blot testing of human HepG2 cell lysate with MRP3 antibody. Predicted molecular weight ~169 kDa but may be observed at higher molecular weights due to glycosylation.

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NSJ-RQ8175-100ug100 ug£535.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Description:
Canalicular multispecific organic anion transporter 2, also called Multidrug resistance-associated protein 3 (MRP3), is a protein that in humans is encoded by the ABCC3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids H22-G1351) was used as the immunogen for the MRP3 antibody.
Purity:
Antigen affinity purified
Uniprot #:
O15438