NSJ Bioreagents

Annexin A1 Antibody

Product Code:
 
NSJ-V9510SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ANXA1/6452R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the Annexin A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 4
IHC staining of FFPE human tonsil tissue with Annexin A1 antibody (clone ANXA1/6452R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
2 / 4
IHC staining of FFPE human tonsil tissue with Annexin A1 antibody (clone ANXA1/6452R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
3 / 4
Western blot testing of human A549 cell lysate using Annexin A1 antibody (clone ANXA1/6452R). Predicted molecular weight ~36 kDa.
4 / 4
SDS-PAGE analysis of purified, BSA-free Annexin A1 antibody (clone ANXA1/6452R) as confirmation of integrity and purity.
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IHC staining of FFPE human tonsil tissue with Annexin A1 antibody (clone ANXA1/6452R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human tonsil tissue with Annexin A1 antibody (clone ANXA1/6452R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Western blot testing of human A549 cell lysate using Annexin A1 antibody (clone ANXA1/6452R). Predicted molecular weight ~36 kDa.
SDS-PAGE analysis of purified, BSA-free Annexin A1 antibody (clone ANXA1/6452R) as confirmation of integrity and purity.

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NSJ-V9510SAF-100UG100 ug£534.00
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Description:
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant full-length human Annexin A1 protein was used as the immunogen for the Annexin A1 antibody.
Localisation:
Nucleus, Cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
P04083