NSJ Bioreagents

IL1 beta Antibody / IL1B

Product Code:
 
NSJ-V9632
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
IL1B/465
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot the IL1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
NSJ-V9632-20UG20 ug£264.00
Quantity:
NSJ-V9632-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
ELISA (order BSA-free format for coating)
Description:
This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Recombinant full-length human IL1B protein was used as the immunogen for the IL1B antibody.
Localisation:
Cytoplasm, Extracellular (secreted)
Purity:
Protein A/G affinity
Uniprot #:
P01584