NSJ Bioreagents

LTF Antibody / Lactoferrin / Lactotransferrin

Product Code:
 
NSJ-V9670
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
LTF/4073
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the LTF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 4
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using LTF antibody (clone LTF/4073). These results demonstrate the foremost specificity of the LTF/4073 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
2 / 4
IHC staining of FFPE human breast tissue with LTF antibody (clone LTF/4073). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
3 / 4
FACS staining of PFA-fixed human MCF-7 cells with LTF antibody (blue, clone LTF/4073) and isotype control (red)
4 / 4
Immunofluorescent staining of PFA-fixed human MCF-7 cells stained using LTF antibody (green, clone LTF/4073) and phalloidin (red).
❮❯

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using LTF antibody (clone LTF/4073). These results demonstrate the foremost specificity of the LTF/4073 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
IHC staining of FFPE human breast tissue with LTF antibody (clone LTF/4073). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
FACS staining of PFA-fixed human MCF-7 cells with LTF antibody (blue, clone LTF/4073) and isotype control (red)
Immunofluorescent staining of PFA-fixed human MCF-7 cells stained using LTF antibody (green, clone LTF/4073) and phalloidin (red).

No additional charges, what you see is what you pay! *

CodeSizePrice
NSJ-V9670-20UG20 ug£264.00
Quantity:
NSJ-V9670-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Show All

Further Information

Application Details:
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Description:
Ferritin and transferrins manage necessary iron-binding functions for iron metabolism. Transferrins comprise a class of single-chain, two-sited, metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin, LTF (lactoferrin) and ovotransferrin. Lactoferrin is found in milk, tears and leukocytes. It degrades an IgA1 protease secreted by Haemophilus influenzae and, consequently, allows the human IgA1antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the transmission of human T cell leukemiavirus type 1, it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 614-645 was used as the immunogen for the LTF antibody.
Localisation:
Cytoplasm, Nuclear, Secreted
Purity:
Protein A/G affinity
Uniprot #:
IDP02788