Recombinant MDM2 Antibody

Product Code:

NSJ-V9675

Product Group:

Primary Antibodies

Supplier:

NSJ Bioreagents

Host Type:

Rabbit

Antibody Isotype:

Rabbit IgG

Antibody Clonality:

Monoclonal

Antibody Clone:

MDM2/7061R

Regulatory Status:

RUO

Target Species:

Human

Application:

Enzyme-Linked Immunosorbent Assay (ELISA)

Storage:

Aliquot the recombinant MDM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

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Code	Size	Price

NSJ-V9675-20UG

20 ug

£264.00

Quantity:

NSJ-V9675-100UG

100 ug

£534.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Application Details:

ELISA (order BSA-free format for coating)

Description:

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers.

Format:

Purified

Formulation:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Immunogen:

A portion of amino acids 126-254 was used as the immunogen for the recombinant MDM2 antibody.

Localisation:

Nuclear

Purity:

Protein A/G affinity

Uniprot #:

Q00987