TargetMol

Apicidin

Product Code:
 
TAR-T14305
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T14305-1mg1mg£311.00
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  • Further Information
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Further Information

Bioactivity:
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, and can be used to study leukemia.
CAS Number:
183506-66-3
Formula:
C34H49N5O6
Molecular Weight:
623.78
Purity:
100%
SMILES:
C(C=1C=2C(N(OC)C1)=CC=CC2)[C@H]3C(=O)N[C@@]([C@H](CC)C)(C(=O)N4[C@@](C(=O)N[C@@H](CCCCCC(CC)=O)C(=O)N3)(CCCC4)[H])[H]
Target:
Apoptosis; HDAC; Autophagy

Documents

References

1.Ahn MY, et al. HDAC inhibitor apicidin suppresses murine oral squamous cell carcinoma cell growth in vitro and in vivo via inhibiting HDAC8 expression. Oncol Lett. 2018 Nov;16(5):6552-6560.