TargetMol

SULT2A1 Protein, Human, Recombinant (His)

Product Code:
 
TAR-TMPY-01587
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPY-01587-50ug50ugEnquire
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  • Further Information
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Further Information

Bioactivity:
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.
Molecular Weight:
35 kDa (predicted)
Purity:
98%

References

1.Chatterjee, B. 2005, Methods Enzymol. 400:165-91. 2.Liu,Y.?et al., 2006, Chem Res Toxicol. 19?(11):1420-5. 3.Sinclair, PA. et al., 2006, J Mol Endocrinol??36?(2):301-11. 4.Yalcin, EB. et al., 2008, Drug Metab Lett??2?(3):198-204.